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Science Desk · NIST · RaDAR program

NIST maps how toxic adulterants in fentanyl vary by region and over time

The study analyzed 4,563 drug-residue samples collected nationwide from January 2024 through June 2026.

Agency release dated 2026-10-08

NIST research chemist Ed Sisco reviews mass spectrometry data from a RaDAR sample
Image: Megan King/NIST (U.S. government work)

What the record says

  • NIST chemist Edward Sisco and colleagues reported the findings in the journal Drug Testing and Analysis.
  • The analysis covered 4,563 samples of drug residues collected nationwide between January 2024 and June 2026.
  • NIST notes most of the adulterants are not opioids and need additional medical treatment; xylazine can cause wounds severe enough to require amputation if untreated.
  • The work is part of NIST’s Rapid Drug Analysis and Research (RaDAR) program.

Source: NIST — NIST Study Shows How the Toxic Substances Mixed Into Fentanyl Vary Across the U.S. and Change Over Time. Notice Nearby summarized this release; it adds no claims beyond the agency record.